Back to Disease Library
bacterium

Columnaris (Cotton Wool Disease)

Skin and gill bacterial infection in warm freshwater fish — fast onset above 25°C.

Severity: moderate
Not OIE-listed
Global, warm-water
Pathogen: Flavobacterium columnare
Species affected: Oreochromis niloticus, Catla catla, Labeo rohita
OIE status: Not OIE-listed
Regions: Global, warm-water

Clinical signs

  • Grey-white, slightly raised patches on the skin — often forming a 'saddleback' lesion across the dorsal fin base
  • Frayed, ragged fins (fin rot) with white margins
  • Pale, swollen, mucus-coated gills (gill rot) — fish gasp at the surface
  • Mouth lesions and erosion around the lips ('cotton-mouth')
  • Lethargy, schooling near aerators, refusal of feed
  • Acute mortality 30–90% in 48–72 hours at >28°C; chronic form spreads over 1–2 weeks at cooler temperatures

Transmission

  • Waterborne — Flavobacterium columnare is endemic in most warm freshwater systems
  • Disease triggered by stress: high temperature (>25°C), high stocking density, low DO, ammonia spikes, handling injuries
  • Direct contact between fish accelerates spread within a pond
  • Mechanical via shared nets, grading boards and transport tanks
  • Virulence rises sharply above 28°C — a 3°C temperature jump can convert latent carriage into an outbreak in 24 hours

Diagnosis

  • Field: saddleback lesion + frayed fins + warm water = high-probability columnaris
  • Microscopy of a skin or gill scrape — long, slender rods that form characteristic 'haystack' columns; gliding motility on the slide
  • Selective culture on Cytophaga agar — yellow, rhizoid colonies
  • Differentiate from Saprolegnia (true cotton-wool tufts, fungal hyphae under microscopy) and Ich (raised round white spots)
  • PCR for the 16S rRNA gene confirms in ambiguous cases

Treatment & emergency response

  • Lower pond temperature 2–3°C where possible (deepen water, increase shade, more aeration)
  • Salt bath at 0.3% (3 g/L) sustained for 7 days — supports osmoregulation in damaged fish and slows bacterial growth
  • Potassium permanganate (KMnO₄) bath at 2 mg/L for a single treatment (consult local regulations; the active dose depends on organic load)
  • Reduce feeding by 50% for 5 days to lower organic load and ammonia
  • Maintain DO above 6 mg/L — damaged gills require more oxygen
  • Increase water exchange (10–15% daily) where biosecurity allows
  • Antibiotics (oxytetracycline, florfenicol) only with a vet prescription, lab sensitivity report, and strict withdrawal-period compliance

Prevention

  • Maintain stocking density within species norms — tilapia outbreaks cluster above 25 fish/m³ in tanks and 5 t/ha in earthen ponds without aeration
  • Avoid water temperatures above 28°C — deepen ponds, add shade nets, run aeration at night
  • Keep ammonia below 0.5 mg/L and DO above 5 mg/L at all times
  • Handle fish only in cool early-morning hours; never grade or net during midday heat
  • Quarantine new fish for 14–21 days; pre-treat with a 3 g/L salt bath before stocking
  • Sanitise transport tanks and grading equipment between batches (KMnO₄ 10 mg/L)
  • Vaccinate tilapia broodstock against columnaris where commercially available (Asia, Latin America)

Biosecurity checklist

  • Foot baths and equipment disinfection at every pond entry
  • Dedicated nets per pond; colour-code to prevent cross-use
  • Daily DO, ammonia and temperature log; spikes trigger pre-emptive salt treatment
  • Pre-stocking salt dip (3 g/L for 15 minutes) for all incoming fingerlings
  • Drain and sun-dry empty ponds for 7+ days between batches
  • Train workers to distinguish saddleback (columnaris) from cotton-wool tufts (saprolegniasis)
  • No grading or transport when forecast water temperature exceeds 28°C for 48 hours

Regional prevalence

See where Columnaris is being reported right now across India and Southeast Asia, with weekly trend lines and per-district drilldowns.

Open the heatmap →

Frequently asked questions

What is columnaris disease in fish?

Columnaris is a bacterial infection caused by Flavobacterium columnare. It primarily attacks the skin, fins and gills of freshwater fish — most aggressively in tilapia, catfish and Indian major carps. The bacterium is endemic in most warm freshwater systems; disease only erupts when fish are stressed by heat, crowding, low DO or handling.

What causes columnaris outbreaks in tilapia ponds?

Three stressors trigger almost every outbreak: water temperature above 28°C, stocking density at or above species limits, and handling injuries from grading or transport. The bacterium is always present in the water — disease begins only when fish immunity drops. Outbreaks above 30°C can move from first symptoms to 70%+ mortality in 48 hours.

How do you treat columnaris in a pond?

Drop pond temperature 2–3°C where possible (deepen water, add shade, increase aeration), apply a 0.3% salt bath sustained for 7 days, cut feed by 50% to reduce organic load, and maintain DO above 6 mg/L. Potassium permanganate at 2 mg/L can be added as a single bath for severe cases. Antibiotics (oxytetracycline, florfenicol) require a vet prescription and strict withdrawal compliance.

Is columnaris the same as fin rot?

Columnaris is a common cause of fin rot, but not the only one. Fin rot is a symptom (frayed, eroded fin margins) that can be caused by columnaris, Aeromonas, Pseudomonas or chronic ammonia stress. A skin scrape under the microscope showing long gliding rods forming haystack columns confirms columnaris specifically.

Can columnaris affect humans?

No. Flavobacterium columnare is a fish-specific pathogen and does not cause disease in humans. Properly handled fish are safe to eat after the standard withdrawal period for any antibiotic used; salt and KMnO₄ treatments do not require a withdrawal period.

How is columnaris different from saprolegniasis?

Columnaris produces flat, grey-white patches with frayed edges — it does not form raised tufts. Saprolegniasis produces true cotton-wool growths that you can lift off the fish with a needle. Under the microscope, columnaris shows long gliding bacterial rods; saprolegniasis shows branching fungal hyphae. Columnaris also tends to attack the gills heavily, while saprolegnia rarely does.

Catch Columnaris before it costs a cycle

CAMARON's Disease Vision module flags Columnaris from a single farm photo, ties findings to the regional heatmap, and walks you through the protocol.